| 18:05 | New York Mets (Santana) (7/8) | New York Yankees (Pettitte)
(15/16) | | View Odds | | 105% |
| 18:05 | Pittsburgh Pirates (Duke) (39/19) | Chicago Cubs (Zambrano)
(5/12) | | View Odds | | 103% |
| 18:10 | Tampa Bay Devil Rays (Garza) (11/10) | St Louis Cardinals (Wainwright)
(4/5) | | View Odds | | 103% |
| 20:55 | Cleveland Indians (Carmona) (13/14) | Cincinnati Reds (Harang)
(10/11) | | View Odds | | 104% |
| 20:55 | Los Angeles Dodgers (Park) (7/5) | Los Angeles Angels (Santana)
(5/8) | | View Odds | | 103% |
| |
| 00:05 | Houston Astros (Oswalt) (5/6) | Texas Rangers (Padilla)
(1) | | View Odds | | 105% |
| 00:05 | Toronto Blue Jays (Burnett) (5/6) | Philadelphia Phillies (Eaton)
(1) | | View Odds | | 105% |
| 00:05 | Washington Nationals (Perez) (10/9) | Baltimore Orioles (Burres)
(10/13) | | View Odds | | 104% |
| 00:10 | Oakland Athletics (Harden) (5/4) | Atlanta Braves (Hudson)
(8/11) | | View Odds | | 102% |
| 00:10 | Kansas City Royals (Bannister) (1) | Florida Marlins (Olsen)
(5/6) | | View Odds | | 105% |
| 01:05 | Minnesota Twins (Hernandez) (11/10) | Colorado Rockies (Reynolds)
(4/5) | | View Odds | | 103% |
| 01:10 | Detroit Tigers (Galarraga) (10/9) | Arizona Diamondbacks (Scherzer)
(10/13) | | View Odds | | 104% |
| 01:35 | Milwaukee Brewers (Suppan) (9/5) | Boston Red Sox (Matsuzaka)
(3/5) | | View Odds | | 98% |
| 02:05 | Chicago White Sox (Buehrle) (14/19) | San Francisco Giants (Zito)
(15/13) | | View Odds | | 104% |
| 03:10 | San Diego Padres (Wolf) (23/17) | Seattle Mariners (Bedard)
(11/17) | | View Odds | | 103% |